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1

Comprehensive mapping of cystic fibrosis mutations to CFTR protein identifies mutation clusters and molecular docking predicts corrector binding site

Molinski, Steven V., Shahani, Vijay M., Subramanian, Adithya S., MacKinnon, Stephen S., Woollard, Geoffrey, Laforet, Marcon, Laselva, Onofrio, Morayniss, Leonard D., Bear, Christine E., Windemuth, And

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2018

Language:

english

File:

PDF, 1.62 MB

english, 2018

2

Influence of soil bulk density and matric potential on microbial dynamics, inorganic N transformations, N2O and N2 fluxes following urea deposition

Hamonts, Kelly, Balaine, Nimlesh, Moltchanova, Elena, Beare, Mike, Thomas, Steve, Wakelin, Steven A., O'Callaghan, Maureen, Condron, Leo M., Clough, Tim J.

Journal:

Soil Biology and Biochemistry

Year:

2013

Language:

english

File:

PDF, 2.04 MB

english, 2013

3

[American Institute of Aeronautics and Astronautics 10th Aerodynamic Decelerator Conference - Cocoa Beach,FL,U.S.A. (18 April 1989 - 20 April 1989)] 10th Aerodynamic Decelerator Conference - New lightweight parachute fabrics of Kevlar aramid fiber

Year:

1989

Language:

english

File:

PDF, 329 KB

english, 1989

4

Optically active solvents in nuclear magnetic resonance spectroscopy. IX. Direct determinations of optical purities and correlations of absolute configurations of .alpha.-amino acids

Pirkle, William H., Beare, Steven D.

Journal:

Journal of the American Chemical Society

Year:

1969

Language:

english

File:

PDF, 670 KB

english, 1969

5

Effects of tillage, compaction and nitrogen inputs on crop production and nitrogen losses following simulated forage crop grazing

Hu, Wei, Beare, Mike, Tregurtha, Craig, Gillespie, Richard, Lehto, Kathryn, Tregurtha, Rebekah, Gosden, Peg, Glasson, Sarah, Dellow, Steven, George, Mike, Tabley, Frank, Qiu, Weiwen, Baird, David

Journal:

Agriculture, Ecosystems & Environment

Year:

2020

Language:

english

File:

PDF, 1.36 MB

english, 2020

6

Catch crops and feeding strategy can reduce the risk of nitrogen leaching in late lactation fodder beet systems

Malcolm, Brendon J., de Ruiter, John M., Dalley, Dawn E., Carrick, Sam, Waugh, Deanne, Arnold, Nathan P., Dellow, Steven J., Beare, Mike H., Johnstone, Paul R., Wohlers, Mark, Brown, Hamish, Welten, B

Journal:

New Zealand Journal of Agricultural Research

Year:

2020

File:

PDF, 3.19 MB

2020

7

Intramolekulare Diels-Alder-Reaktion vom Typ 2: Synthese und Chemie von Brückenkopf-Alkenen

Brian R. Bear, Steven M. Sparks, Kenneth J. Shea

Journal:

Angewandte Chemie

Year:

2001

Language:

german

File:

PDF, 615 KB

german, 2001

8

The Type 2 Intramolecular Diels–Alder Reaction: Synthesis and Chemistry of Bridgehead Alkenes

Brian R. Bear, Steven M. Sparks, Kenneth J. Shea

Journal:

Angewandte Chemie International Edition

Year:

2001

Language:

english

File:

PDF, 608 KB

english, 2001

9

ChemInform Abstract: The Type 2 Intramolecular Diels—Alder Reaction: Synthesis and Chemistry of Bridgehead Alkenes

Brian R. Bear, Steven M. Sparks, Kenneth J. Shea

Journal:

Year:

2001

File:

PDF, 25 KB

2001

10

Techniques for Studying Biliary Secretion: Electrolytes in Bile

Christine E. Bear, Steven M. Strasberg

Journal:

Year:

1984

Language:

english

File:

PDF, 775 KB

english, 1984

11

Evidence for a channel for the electrogenic transport of chloride ion in the rat hepatocyte

Christine E. Bear, Connie N. Petrunka, Steven M. Strasberg

Journal:

Year:

1985

Language:

english

File:

PDF, 991 KB

english, 1985

12

Do surgical oncologists achieve lower rates of local-regional recurrence in node positive breast cancer treated with mastectomy alone?

Steven Latosinsky, Harry D. Bear

Journal:

Journal of Surgical Oncology

Year:

2001

Language:

english

File:

PDF, 96 KB

english, 2001

13

Optimisation of a parallel ocean general circulation model

M. I. Beare, D. P. Stevens

Journal:

Annales Geophysicae

Year:

1997

Language:

english

File:

PDF, 1.24 MB

english, 1997

14

Disparities Between Ambient, Standard Lighting and Retinal Acuities in Community-Dwelling Older People: Implications for Disability

Steven M. Albert, Jane Bear-Lehman, Ann Burkhardt

Journal:

Journal of the American Geriatrics Society

Year:

2006

Language:

english

File:

PDF, 81 KB

english, 2006

15

Relevance of Race and Ethnicity for Self-Reported Functional Limitation

S. Melinda Spencer, Steven M. Albert, Jane Bear-Lehman, Ann Burkhardt

Journal:

Journal of the American Geriatrics Society

Year:

2008

Language:

english

File:

PDF, 92 KB

english, 2008

16

Evaluation of stereotactic core needle biopsy (SCNB) of the breast at a single institution

Steven Latosinsky, David Cornell, Harry D. Bear, Stephen E. Karp, Sherrill Little, EllenDe Paredes

Journal:

Breast Cancer Research and Treatment

Year:

2000

Language:

english

File:

PDF, 45 KB

english, 2000

17

Identification of a P-Glycoprotein-Deficient Subpopulation in the CF-1 Mouse Strain Using a Restriction Fragment Length Polymorphism

Diane R. Umbenhauer, George R. Lankas, Todd R. Pippert, L.David Wise, Mark E. Cartwright, Steven J. Hall, Carolann M. Beare

Journal:

Toxicology and Applied Pharmacology

Year:

1997

Language:

english

File:

PDF, 194 KB

english, 1997

18

Role of delta opioid efficacy as a determinant of mu/delta opioid interactions in rhesus monkeys

S. Stevens Negus, Ashley E. Bear, John E. Folk, Kenner C. Rice

Journal:

European Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 333 KB

english, 2009

19

Heparin-binding and patterns of virulence for two recombinant strains of Sindbis virus

J. Steven Bear, Andrew P. Byrnes, Diane E. Griffin

Journal:

Year:

2006

Language:

english

File:

PDF, 361 KB

english, 2006

20

Chemometrics

Brown, Steven D., Bear, Robert S., Blank, Thomas B.

Journal:

Analytical Chemistry

Year:

1992

Language:

english

File:

PDF, 5.47 MB

english, 1992

21

Poster 13: Validation of the assessment of motor and process skills among older adults in the community

Steven M. Albert, Ann Burkhardt, Jane Bear-Lehman

Journal:

Archives of Physical Medicine and Rehabilitation

Year:

2003

Language:

english

File:

PDF, 27 KB

english, 2003

22

Genome-Wide Analysis of MEF2 Transcriptional Program Reveals Synaptic Target Genes and Neuronal Activity-Dependent Polyadenylation Site Selection

Steven W. Flavell, Tae-Kyung Kim, Jesse M. Gray, David A. Harmin, Martin Hemberg, Elizabeth J. Hong, Eirene Markenscoff-Papadimitriou, Daniel M. Bear, Michael E. Greenberg

Journal:

Year:

2008

Language:

english

File:

PDF, 1.43 MB

english, 2008

23

Outcome study of cholecystectomy during pregnancy

James E Barone, Sean Bears, Steven Chen, John Tsai, John C Russell

Journal:

The American Journal of Surgery

Year:

1999

Language:

english

File:

PDF, 136 KB

english, 1999

24

Segmentation of the mouse hippocampal formation in magnetic resonance images

Kay Richards, Charles Watson, Rachel F. Buckley, Nyoman D. Kurniawan, Zhengyi Yang, Marianne D. Keller, Richard Beare, Perry F. Bartlett, Gary F. Egan, Graham J. Galloway, George Paxinos, Steven Petro

Journal:

Year:

2011

Language:

english

File:

PDF, 1.35 MB

english, 2011

25

Membership application

Hamonts, Kelly, Balaine, Nimlesh, Moltchanova, Elena, Beare, Mike, Thomas, Steve, Wakelin, Steven A., O'Callaghan, Maureen, Condron, Leo M., Clough, Tim J.

Journal:

Academic Radiology

Year:

1998

File:

PDF, 35 KB

1998

26

An Approach to the Identification of Anomalies and Etiologies in Neonates with Identified or Suspected VACTERL (Vertebral Defects, Anal Atresia, Tracheo-Esophageal Fistula with Esophageal Atresia, Cardiac Anomalies, Renal Anomalies, and Limb Anomalies) Association

Solomon, Benjamin D., Baker, Linda A., Bear, Kelly A., Cunningham, Bridget K., Giampietro, Philip F., Hadigan, Colleen, Hadley, Donald W., Harrison, Steven, Levitt, Marc A., Niforatos, Nickie, Paul, S

Journal:

The Journal of Pediatrics

Year:

2014

Language:

english

File:

PDF, 861 KB

english, 2014

27

Tetrahydrofuran decomposition. Condensation of solvent fragment with benzophenone and trityllithium

Tomboulian, Paul, Amick, David, Beare, Steven, Dumke, Kay, Hart, Douglas, Hites, Ronald, Metzger, Anita, Nowak, Robert

Journal:

Journal of Organic Chemistry

Year:

1973

Language:

english

File:

PDF, 549 KB

english, 1973

28

Optically active solvents for nuclear magnetic resonance. X. Enantiomeric nonequivalence of sulfinamides, sulfinates, sulfites, thiosulfinates, phosphine oxides, and amine oxides

Pirkle, William H., Beare, Steven D., Muntz, Ronald L.

Journal:

Journal of the American Chemical Society

Year:

1969

Language:

english

File:

PDF, 119 KB

english, 1969

29

Nonequivalence of the nuclear magnetic resonance spectra of enantiomers in optically active solvents. IV. Assignment of absolute configuration

Pirkle, William H., Beare, Steven D.

Journal:

Journal of the American Chemical Society

Year:

1967

Language:

english

File:

PDF, 354 KB

english, 1967

30

Ultrasonic pulse method with nonlinear calibration for quantitative monitoring of polymer blends over a wide temperature range

Bear, Robert S., Brown, Steven D.

Journal:

Analytical Chemistry

Year:

1993

Language:

english

File:

PDF, 544 KB

english, 1993

31

The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor

Broadbent, Steven D., Ramjeesingh, Mohabir, Bear, Christine E., Argent, Barry E., Linsdell, Paul, Gray, Michael A.

Journal:

Pflügers Archiv European Journal of Physiology

Year:

2015

Language:

english

File:

PDF, 1.29 MB

english, 2015

32

Kalman filter-optimized simulation for step voltammetry

Bear, Robert S., Brown, Steven D.

Journal:

Analytical Chemistry

Year:

1993

Language:

english

File:

PDF, 983 KB

english, 1993

33

Optically active nuclear magnetic resonance solvents. VIII. Resolution of 2,2,2-trifluoro-1-phenylethanol

Pirkle, William H., Beare, Steven D., Burlingame, T. G.

Journal:

Journal of Organic Chemistry

Year:

1969

Language:

english

File:

PDF, 315 KB

english, 1969

34

Genetic, cell biological, and clinical interrogation of the CFTR mutation c.3700 A>G (p.Ile1234Val) informs strategies for future medical intervention

Molinski, Steven V., Gonska, Tanja, Huan, Ling Jun, Baskin, Berivan, Janahi, Ibrahim A., Ray, Peter N., Bear, Christine E.

Journal:

Genetics in Medicine

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014

35

The major cystic fibrosis causing mutation exhibits defective propensity for phosphorylation

Pasyk, Stan, Molinski, Steven, Ahmadi, Saumel, Ramjeesingh, Mohabir, Huan, Ling-Jun, Chin, Stephanie, Du, Kai, Yeger, Herman, Taylor, Paul, Moran, Michael F., Bear, Christine E.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.16 MB

english, 2015

36

Conformational defects underlie proteasomal degradation of Dent's disease-causing mutants of ClC-5

D’Antonio, Christina, Molinski, Steven, Ahmadi, Saumel, Huan, Ling‑Jun, Wellhauser, Leigh, Bear, Christine E.

Journal:

Biochemical Journal

Year:

2013

Language:

english

File:

PDF, 921 KB

english, 2013

37

Replication-Competent Retroviruses in Gene-Modified T Cells Used in Clinical Trials: Is It Time to Revise the Testing Requirements?

Bear, Adham S, Morgan, Richard A, Cornetta, Kenneth, June, Carl H, Binder-Scholl, Gwendolyn, Dudley, Mark E, Feldman, Steven A, Rosenberg, Steven A, Shurtleff, Sheila A, Rooney, Cliona M, Heslop, Hele

Journal:

Molecular Therapy

Year:

2012

Language:

english

File:

PDF, 239 KB

english, 2012

38

Identification and Validation of Hits from High Throughput Screens for CFTR Modulators

Pasyk, Stan, Molinski, Steven, Yu, Wilson, D.W. Eckford, Paul, E. Bear, Christine

Journal:

Current Pharmaceutical Design

Year:

2012

Language:

english

File:

PDF, 933 KB

english, 2012

39

Mild depressive symptoms, self-reported disability, and slowing across multiple functional domains

Albert, Steven M., Bear-Lehman, Jane, Burkhardt, Ann

Journal:

International Psychogeriatrics

Year:

2012

Language:

english

File:

PDF, 115 KB

english, 2012

40

Cutaneous Sensitivity and Functional Limitation

Bear-Lehman, Jane, Albert, Steven M., Burkhardt, Ann

Journal:

Topics in Geriatric Rehabilitation

Year:

2006

Language:

english

File:

PDF, 84 KB

english, 2006

41

Bryostatin 1 activates splenic lymphocytes and induces sustained depletion of splenocyte protein kinase C activity in vivo after a single intravenous administration

Bear, Harry D, McFadden, Andrew WJ, Kostuchenko, Paul J, Lipshy, Kenneth A, Hamad, Giselle G, Turner, Amy J, Roberts, John D, Carr, Marcus, Carr, Sheryl, Grant, Steven

Journal:

Anti-Cancer Drugs

Year:

1996

File:

PDF, 640 KB

1996

42

The investigational Cystic Fibrosis drug Trimethylangelicin directly modulates CFTR by stabilizing the first membrane-spanning domain

Laselva, Onofrio, Molinski, Steven, Casavola, Valeria, Bear, Christine E.

Journal:

Biochemical Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.50 MB

english, 2016

43

Attenuation of Phosphorylation-dependent Activation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by Disease-causing Mutations at the Transmission Interface

Chin, Stephanie, Yang, Donghe, Miles, Andrew J., Eckford, Paul D. W., Molinski, Steven, Wallace, B. A., Bear, Christine E.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 1.83 MB

english, 2017

44

Using the 21-gene assay from core needle biopsies to choose neoadjuvant therapy for breast cancer: A multicenter trial

Bear, Harry D., Wan, Wen, Robidoux, André, Rubin, Peter, Limentani, Steven, White, Richard L., Granfortuna, James, Hopkins, Judith O., Oldham, Dwight, Rodriguez, Angel, Sing, Amy P.

Journal:

Journal of Surgical Oncology

Year:

2017

Language:

english

File:

PDF, 388 KB

english, 2017

45

New mechanisms of resistance to MEK inhibitors in melanoma revealed by intravital imaging

Brighton, Hailey E, Angus, Steven P, Bo, Tao, Roques, Jose, Tagliatela, Alicia C, Darr, David, Karagoz, Kubra, Sciaky, Noah, Gatza, Michael, Sharpless, Norman E., Johnson, Gary L., Bear, James E.

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 9.99 MB

english, 2017

46

Correctors of the major Cystic Fibrosis mutant interact through membrane spanning domains

Laselva, Onofrio, Molinski, Steven, Casavola, Valeria, Bear, Christine E.

Journal:

Molecular Pharmacology

Year:

2018

Language:

english

File:

PDF, 3.65 MB

english, 2018

47

Re: Using the 21-gene assay from core needle biopsies to choose neoadjuvant therapy for breast cancer: A multicenter trial. Journal of Surgical Oncology 2017;115(8):917-923.

Bear, Harry D., Wan, Wen, Robidoux, André, Rubin, Peter, Limentani, Steven, White, Richard L., Granfortuna, James, Hopkins, Judith O., Oldham, Dwight, Rodriguez, Angel, Sing, Amy P.

Journal:

Journal of Surgical Oncology

Year:

2017

Language:

english

File:

PDF, 197 KB

english, 2017

48

Functional Rescue of F508del-CFTR Using Small Molecule Correctors

Molinski, Steven, Eckford, Paul D. W., Pasyk, Stan, Ahmadi, Saumel, Chin, Stephanie, Bear, Christine E.

Journal:

Frontiers in Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.50 MB

english, 2012

49

Cover Image, Volume 86, Issue 8

Molinski, Steven V., Shahani, Vijay M., Subramanian, Adithya S., MacKinnon, Stephen S., Woollard, Geoffrey, Laforet, Marcon, Laselva, Onofrio, Morayniss, Leonard D., Bear, Christine E., Windemuth, And

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2018

File:

PDF, 1.31 MB

2018

50

Activity of lumacaftor is not conserved in zebrafish Cftr bearing the major cystic fibrosis‐causing mutation

Laselva, Onofrio, Erwood, Steven, Du, Kai, Ivakine, Zhenya, Bear, Christine E.

Journal:

FASEB BioAdvances

Year:

2019

Language:

english

File:

PDF, 694 KB

english, 2019